It is not like ‘very limited’. But generally they are focused around modern Intel CPU, and can have issues on new AMD CPU. And it won’t work on very old CPUs without proper virtualization features.
https://www.qubes-os.org/hcl/ can hint on what Qubes will work better.
Also see the system requirements: https://www.qubes-os.org/doc/system-requirements/
But we (will) have ‘Grave of the Fireflies’ at home…