• 21 Posts
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Joined 3 years ago
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Cake day: July 6th, 2023

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  • drastically changing the heat and or humidity in your house is going to be a bad experience. You’re much better off getting a cheap sauna bag, and using that to heat up. Just your body. Typical sauna temperatures are between 70° c and 90° c.

    In a traditional sauna I’ve melted water bottles and glasses, most things in a kitchen are not designed to get so hot.


  • Over a billion users, and very popular in old eastern bloc countries already.

    Yes central control, and controlled by people who don’t have the most robust encryption or opsec (CEO house arrest in France for example)… But over time they have demonstrated they don’t care too much about most low level crimes.

    So it’s in the sweet spot of good enough and convenient but not great and not perfect











  • Almost all checkups do a lipid panel. You just have to look at your triglycerides and your HDL, take the ratio of them TG over HDL. You want that to be less than two, and for bonus points you want that to be less than one. Anything above two you have room for improvement. This ratio is a fairly good analog for insulin sensitivity and metabolic health.

    Signs of poor metabolic health:

    • obesity
    • high blood pressure
    • Ed
    • snoring
    • fatty liver
    • skin tags
    • diabetes

  • The problem with a lot of these papers is they use intermediate endpoints rather than actual hard end points. They’re making the assumption that decreasing LDL is a good thing. That’s an intermediate endpoint, nobody actually cares about their LDL, they care about their health span and lifespan.

    Spoiler: LDL and Cholesterol in general is not a disease, it’s poor metabolic health that is the actual cardiovascular problem.

    I.e. https://doi.org/10.3390/metabo14010073 Oreo cookie treatment lowers LDL cholesterol more than high-intensity statin therapy in a lean mass hyper-responder on a ketogenic diet: a curious crossover experiment

    This stunt paper illustrates how silly it is to focus on a intermediate metric. Oreos are not health food, I should hope that is obvious


  • My LDL is the only thing wrecking my score.

    Cholesterol, and LDL specifically, are not a disease. If you’re metabolically healthy, LDL is good for you. Check your insulin sensitivity (homa-ir, or tg/HDL ratio, or fasting insulin) to see what type of ldl you have.

    Cholesterol is necessary. You will die without cholesterol. Cholesterol is produced in the liver, delivers fat throughout the body, and then gets recycled in the liver. If something damages the cholesterol during this process, oxidation, or glycation, the LDL will not be recycled by the liver. This is one of the patterns of elevated LDL, it’s the damage LDL that’s the problem, it’s the systematic damage in your body. The LDL isn’t the fault. It’s a symptom. If your LDL isn’t damaged (as seen by insulin sensitivity) then it’s really not a problem.





  • Conference meeting test: you and a bunch of strangers gather for a quick q&a after a conference talk, the author wants to share their slidedeck with you. Everyone has whatever solution you are evaluating pre installed but your strangers so you have nothing setup specifically for this group… How many button presses across everyone does it take to share the slides?

    Wait, I don’t see you. Are you on the conference wifi? No I’m on call data, join the conference wifi. What’s the password. Ok. Thanks. I joined it, I don’t see the file. Which wifi are you on? Oh I’m on 5g. This is too complicated join my hot spot. Fuck I can’t see your hotspot, turn airplane mode on and off. I joined it but I don’t see anyone…